ZeeST Bio company logo with a stylized flower symbol in blue.

Precision Targeting for Liver Cancer Therapeutics

Leveraging clinically validated hepatotropic mechanisms
to enable tumor-selective delivery of therapeutic payloads.

“¢ Clinically validated liver-targeting approach
“¢ Dual imaging and therapeutic platform
“¢ Designed for tumor retention


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Our Approach

We are developing a radiotheranostic platform that uses clinically validated liver-targeting biology to deliver radioactive payloads to tumors.

By leveraging endogenous hepatic transport mechanisms, our approach is designed to enable tumor targeting while supporting clearance from normal tissue.

Pipeline

Lead Program – Radiotherapeutic platform – Preclinical
Imaging Agent – Diagnostic platform – Preclinical

Our platform is designed to enable expansion into additional malignancies.

Team

Khashayar Vakili, M.D.

Founder, Chief Executive Officer & Chief Scientific Officer

Hepatobiliary and liver transplant surgeon with over 15 years of experience in liver cancer biology and translational research, with a focus on developing novel therapeutic approaches for liver malignancies.

Scientific Advisors

Alan Packard, Ph.D. – Boston Children’s Hospital & Harvard Medical School

Anthony Belanger, Ph.D. – Dana Farber Cancer Institute & Harvard Medical School

Caroline Benn, Ph.D. – LoQus23 Therapeutics

Momentum

Building toward clinical translation

Selected for MassChallenge Healthcare Traction Program 2026
Supported by National Cancer Institute / NIH funding

Partner with us

We are seeking strategic partners and investors to advance our platform toward clinical development.

contact@zeest.bio